制定者：辛辛那提儿童医院医疗中心(CCHMC,Cincinnati Children's Hospital Medical Center)
摘要：For this guideline, NEC is classified according to Bell's clinical staging (see Appendix) (Bell 1978 [4b]). Population-based estimates of NEC range from 0.72 to 2.4 cases per 1,000 live births (Holman 2006 [4a], Llanos 2002 [4a]). In-hospital case fatality rates are approximately 16% to 20% (Holman 2006 [4a]).Case fatality rates are higher in very low birth weight (VLBW) infants, infants with more severe disease, and infants requiring surgery (Holman 2006 [4a], Lin 2008 [5a]).NEC-associated morbidities, including short bowel syndrome, contribute significantly to poor growth and neurodevelopmental outcomes and to increased health-care costs (Schulzke 2007 [1b], Vohr 2000 [2b], Salhab 2004 [4a], Bisquera 2002 [4a], Goulet 2004 [5b]).
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