文章类型：指南原文

语言：英文

中文标题：2014 CPS立场声明：儿童艰难梭菌感染

英文标题：Clostridium difficile in paediatric populations.

制定者：加拿大儿科学会(CPS,Canadian Paediatric Society)

制定日期：2014.1.30

摘要：An increase in Clostridium difficile infection incidence has been observed among hospitalized children in the United States. The present statement, targeted at clinicians caring for infants and children in community and institutional settings, summarizes the relevant information relating to the role of C difficile in childhood diarrhea and provides recommendations for diagnosis, prevention and treatment. Significant differences between adult and paediatric risk factors and disease are discussed, along with emerging therapies. The relationship between age and disease severity in children with a newly emergent and more fluoroqinolone-resistant strain of C difficile (North American Pulse-field type-1 [NAP1]) remains unknown. The importance of antimicrobial stewardship as a preventive strategy is highlighted. This statement replaces a previous Canadian Paediatric Society position statement
on C difficile published in 2000.

关键词：CDI; Colitis; Diarrhea; Immunocompromise; Megacolon; Metronidazole; NAP1; Vancomycin

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